Supplemental Information A Host Ca/Mn Ion Pump Is a Factor in the Emergence of Viral RNA Recombinants
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منابع مشابه
A host Ca2+/Mn2+ ion pump is a factor in the emergence of viral RNA recombinants.
Viruses change rapidly due to genetic mutations, and viral RNA recombination in RNA viruses can lead to the emergence of drug-resistant or highly virulent strains. Here, we report that host Pmr1p, an ion pump that controls Ca2+/Mn2+ influx into the Golgi from the cytosol, affects the frequency of viral RNA recombination and the efficiency of replication. Inactivation of PMR1 leads to an approxi...
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